Stimbiotic supplementation modulated intestinal inflammatory response and improved boilers performance in an experimentally-induced necrotic enteritis infection model

Autor: Ji Hwan Lee, Byongkon Lee, Xavière Rousseau, Gilson A. Gomes, Han Jin Oh, Yong Ju Kim, Se Yeon Chang, Jae Woo An, Young Bin Go, Dong Cheol Song, Hyun Ah Cho, Jin Ho Cho
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Animal Science and Biotechnology, Vol 13, Iss 1, Pp 1-17 (2022)
Druh dokumentu: article
ISSN: 2049-1891
DOI: 10.1186/s40104-022-00753-9
Popis: Abstract Background Two experiments were conducted to establish an optimal NE challenge model and evaluate the efficacy of stimbiotic (STB) supplementation in necrotic enteritis (NE) challenged broilers. In Exp. 1, a total of 120 Arbor Acres (AA) broilers (45.0 ± 0.21 g) were randomly assigned to 6 treatments in a 3 × 2 factorial arrangement. Vaccine treatments included non-challenge (0), × 10 the recommended dose (× 10) or × 20 the recommended dose (× 20) by the manufacturer. Clostridium perfringens (CP) treatments were non-challenge (No) or 3 mL of 2.2 × 107 CFU CP challenge (Yes). In Exp. 2, a total of 72 AA broilers (40.17 ± 0.27 g) were randomly assigned to 6 treatments in a 3 × 2 factorial arrangement. Dietary treatments included non-additive (CON), 100 mg/kg STB (STB) and 100 mg/kg STB on top of a typical commercial blend including an essential oil, probiotics, and enzyme (CB). Challenge treatments included non-NE challenge (No) and NE challenge (Yes) as established in Exp. 1. Results In Exp. 1, CP and vaccine challenge decreased (P
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