Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations

Autor: Liting Zhai, Lingling Feng, Lin Xia, Huiyong Yin, Song Xiang
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms11229
Popis: Debranching of glycogen is an important step in its use as an energy source. Here, the authors describe the crystal structures of glycogen debranching enzyme alone and in complex with oligosaccharides and provide molecular insights into the function, and into associated diseases.
Databáze: Directory of Open Access Journals