| Autor: |
Yoshimasa Kitagawa, Noritaka Ohga, Takuya Asaka, Jun Sato, Hironobu Hata, Joseph Helman, Kanako Tsuboi, Norio Amizuka, Yuji Kuge, Tohru Shiga |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Japanese Dental Science Review, Vol 55, Iss 1, Pp 65-70 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1882-7616 |
| DOI: |
10.1016/j.jdsr.2018.12.001 |
| Popis: |
Summary: Medication-related osteonecrosis of jaws (MRONJ) is one of the most complicated inflammatory conditions in oral and maxillofacial region. It is very difficult to correctly evaluate the degree and extent of necrosis and infection. This refractory osteonecrosis often needs extended surgery, leading to impaired quality-of-life. We have performed hyperbaric oxygen therapy (HBO) combined with conservative surgery for advanced cases. We have appraised the value of FDG-PET and 3-phase bone scintigraphy in the diagnosis and management of this condition. MRONJ showed significantly higher SUVmax on FDG-PET than the others. Although the 3 phase pool bone images did not change significantly, perfusion and static bone image as well as PET showed remarkable response to HBO for MRONJ. SUVmax after HBO was significantly lower than those of before HBO. These preliminary results indicate that FDG-PET is useful for monitoring the effect of HBO for MRONJ. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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