Granulomatous intersticial nephritis secondary to sarcoidosis

Autor: Tamires Teixeira Piraciaba, Carlos Alberto Balda, Luiz Antônio Ribeiro de Moura, Carlos Alberto de Castro Pereira, Gianna Mastroianni Kirsztajn
Jazyk: English<br />Portuguese
Předmět:
Zdroj: Brazilian Journal of Nephrology, Vol 39, Iss 4, Pp 473-476
Druh dokumentu: article
ISSN: 2175-8239
0101-2800
DOI: 10.5935/0101-2800.20170084
Popis: ABSTRACT Introduction: Granulomatous interstitial nephritis is a rare condition, in which renal involvement is uncommon. Its etiology is variable, and may be medicinal, infectious or inflammatory origin. Case report: This is a 65-year-old male patient with renal lesions of unknown etiology, associated with hypercalcaemia. During the investigation, cardiac insufficiency with diastolic dysfunction and interstitial lung involvement on chest tomography were evidenced. Renal function (glomerular filtration rate) has partially improved with clinical measures. Renal biopsy was performed, which showed moderate interstitial lesion with tuberculoid granulomas without caseous necrosis. Conclusion: The objective of the article was to describe a case of NIG and to alert to the importance of its clinical investigation. In this case, renal biopsy, associated with systemic clinical manifestations, contributed to the diagnosis of sarcoidosis.
Databáze: Directory of Open Access Journals