Severe gastrointestinal involvement in pediatric IgA vasculitis: a retrospective single-center cohort study in China

Autor: Yifan Li, Xiaomei Zhang, Haimei Liu, Guomin Li, Wanzhen Guan, Tao Zhang, Qiaoqian Zeng, Yinv Gong, Hong Xu, Li Sun
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Pediatrics, Vol 11 (2023)
Druh dokumentu: article
ISSN: 2296-2360
DOI: 10.3389/fped.2023.1194214
Popis: ObjectivesThe study aimed to describe the characteristics of gastrointestinal (GI) involvement in a cohort of hospitalized children with IgA vasculitis (IgAV) in China.MethodWe reviewed the records of hospitalized IgAV patients from January 2014 to December 2020 at one tertiary medical center. The patients were divided into the severe GI group and the non-severe GI group according to the presence of massive GI bleeding and complications. The clinical manifestations, laboratory factors, and treatment were analyzed between the two groups.ResultsA total of 1,179 patients were hospitalized due to IgAV. GI involvement was noted in 50% (589) of the patients, of whom 288 (48.9%) had severe GI involvement. GI complications were observed in 34 patients with IgAV with GI involvement. Rare onset age (
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