A Case of Persistent Bacillus cereus Bacteremia Responding to a Combination of Vancomycin and Gentamicin

Autor:	Hiroshi Sasano, Toshihiro Yoshizawa, Mai Suzuki, Yukiko Fukui, Ryutarou Arakawa, Naoto Tamura, Toshio Naito
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Infectious and parasitic diseases RC109-216
Zdroj:	Case Reports in Infectious Diseases, Vol 2022 (2022)
Druh dokumentu:	article
ISSN:	2090-6633
DOI:	10.1155/2022/8725102
Popis:	A 56-year-old woman with a history of connective tissue disease developed fever, and Bacillus cereus (B. cereus) was detected in blood cultures. Therefore, treatment with vancomycin (VCM) was initiated. Since her blood cultures persistently detected B. cereus despite peripheral intravenous catheter replacement and VCM treatment, concomitant treatment with gentamicin (GM) was started. Blood cultures then became negative. Persistent B. cereus bacteremia responded to combination therapy with VCM and GM. This combination therapy may increase the risk of developing renal dysfunction, but the risk can be mitigated by appropriate therapeutic drug monitoring (TDM) and dose adjustments to achieve successful treatment.
Databáze:	Directory of Open Access Journals
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