Immediate Breast Reconstruction Outcomes in Patients with Prior Mantle and Whole Breast Irradiation

Autor: Barbara L. Mullen, MD, Muhammad S. Mazroua, MBBCh, Brenna M. Murphy, MD, Thanapoom Boonipat, MD, Robert W. Gao, MD, Mary M. Mrdutt, MD, MS, Dean A. Shumway, MD, Amy C. Degnim, MD, Aparna Vijayasekaran, MBBS
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss 9, p e6121 (2024)
Druh dokumentu: article
ISSN: 2169-7574
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DOI: 10.1097/GOX.0000000000006121
Popis: Background:. Limited studies have detailed the risk of mastectomy with immediate breast reconstruction among women who previously received mantle field radiation. Methods:. A single institution retrospective review from 2010 to 2020 of patients previously treated with mantle field radiation (MF-RT) and subsequent mastectomy with immediate breast reconstruction was performed. Patients with prior whole breast irradiation (WBI) were also included as a reference group. Demographic, comorbidity, and surgical factors were collected. The primary outcome was major complications, defined as those requiring reoperation, intravenous antibiotics, or debridement. Results:. Fourteen patients with prior MF-RT (27 breasts) and 129 with prior WBI (132 breasts) underwent mastectomy with immediate reconstruction. Prior MF-RT patients were significantly younger (43.8 versus 57.5, P
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