Evaluation of the nutritional index and immunological function of a fermented vegetable for esophageal cancer patients undergoing immunotherapy plus chemotherapy: A randomized controlled trial

Autor: Nan Lin, Tingting Dai, Jing Zhou, Hexiao Huang, Hong Yun, Zhenyu Ding, Xuelei Ma
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Functional Foods, Vol 99, Iss , Pp 105350- (2022)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2022.105350
Popis: Fermented food has been demonstrated to increase immunity, protect against pathogens, and improve cancer survival. However, the relationship between fermented vegetables and immunotherapy has not been tested. We conducted a randomized controlled trial. The experimental group (n = 36) was supplemented with fermented vegetable enzyme every day for 2 cycles of immunotherapy, while the control group (n = 36) received a normal diet. The treatment response, nutritional and immunological indexes were collected at baseline and after 2 cycles of therapy. After comparing the baseline and the follow-up CT, no significant difference was found between the two groups. The hemoglobin, FT4, AST, albumin, LDL-C, and IgG indexes were better in the experimental group, meaning the side effects of immunotherapy in esophageal cancer patients. Fermented foods can alleviate the side effects of esophageal cancer immunotherapy combined with chemotherapy to a certain extent, such as anemia, malnutrition, and elevated AST.
Databáze: Directory of Open Access Journals