Analysis of antibiotic strategies to prevent vascular graft or endograft infection after surgical treatment for infective native aortic aneurysms: a systematic review

Autor: Shye-Jao Wu, Shen Sun, Yu-Hern Tan, Chen-Yen Chien
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Antimicrobial Resistance and Infection Control, Vol 13, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 2047-2994
DOI: 10.1186/s13756-024-01477-3
Popis: Abstract Introduction Some patients with an infective native aortic aneurysm (INAA) develop an aortic vascular graft or endograft infection (VGEI) even after successful open surgical repair or endovascular intervention. The aim of the systematic review and meta-analysis performed herein was to compare the clinical outcomes of different surgical and antibiotic treatment strategies. Methods We systematically searched PubMed, MEDLINE, EMBASE and Web of Science. The keywords used for the search were “mycotic aortic aneurysm”, “infected aortic aneurysm”, “infective native aortic aneurysm”, “antibiotics”, “surgery”, and “endovascular”. The search was limited to articles written in English and to studies involving humans. Articles published before 2000 were excluded. Case reports and review articles were excluded. Results Of the 524 studies retrieved from our search of the databases, 47 articles were included in this study. Among the 47 articles (1546 patients, 72.8% of whom were male) retrieved, five articles were excluded from the subgroup analysis because the data concerning open surgical repair and endovascular intervention could not be separated. The remaining 42 articles included a total of 1179 patients who underwent open surgical repair (622 patients) or endovascular intervention (557 patients) for INAA. There was a statistically significant difference (p = 0.001) in the pooled in-hospital mortality rate between the open surgical repair group (13.2%, 82/622) and the endovascular intervention group (7.2%, 40/557). However, there was a statistically significant difference (p
Databáze: Directory of Open Access Journals
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