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Guillermo Salcedo-Villanueva,1 Abraham Alejandro Medina-Andrade,1 Daniel Moreno-Paramo,2 Maria Fernanda Golzarri,1 Edel Moreno-Paramo,1 Grecia Yael Ortiz-Ramirez,1 Ursula Martinez-Aguilar,3 Ulises De Dios-Cuadras,3 Martin Jimenez-Rodriguez,4 Itzel Espinosa-Soto,4 Ximena Mira-Lorenzo,5 Juvenal Guzman-Cerda,5 Andres Orozco-Moguel,6 Catalina Becerra-Revollo,1 Luis Porfirio Orozco-Gomez,7 Emiliano Fulda3 1Retina Department, Asociación Para Evitar la Ceguera en México, Hospital “Dr. Luis Sánchez Bulnes”, Mexico City, Mexico; 2Ophthalmology Department, Hospital General de México “Dr. Eduardo Liceaga”, Mexico City, Mexico; 3Retina Department, Instituto de Oftalmología Fundación Conde de Valenciana, Mexico City, Mexico; 4Retina Department, Fundación Hospital Nuestra Señora de la Luz, Mexico City, Mexico; 5Retina Department, Instituto Mexicano de Oftalmología, Santiago de Queretaro, Mexico; 6Facultad de Medicina, Universidad Nacional Autónoma de México; 7Retina Department, Centro Médico Nacional 20 de Noviembre, Mexico City, MexicoCorrespondence: Guillermo Salcedo-Villanueva RetinaDepartment, Asociación Para Evitar la Ceguera en México, Hospital “Dr Luis Sánchez Bulnes”, IAP, Vicente García Torres 46, Col. San Lucas, Coyoacan, Mexico City, CP 04030, MexicoTel +52 55 10841400, Ext 1172Email guillermo.salcedo@apec.com.mxPurpose: To describe the primary cancer sites and clinical features of choroidal metastasis in Mexican patients.Methods: This was a retrospective, observational, and multi-center study. Data were recollected from 6 ophthalmological hospitals in Mexico from patients with choroidal metastasis diagnosed from 2000 to 2018.Results: Seventy-eight patients were studied: 43 were female and 35 were male. Mean age at presentation was 57.6 years. Overall, primary cancer sites were: 1) breast: 27 cases (34.6%); 2) lung: 19 cases (24.3%); 3) unknown: 8 cases (10.2%); 4) gastrointestinal: 7 cases (8.9%); 5) renal: 5 cases (6.4%); 6) testicular: 3 cases (3.8%); 7) ovary: 3 Cases (3.8%); 8) prostate: 2 cases (2.5%); 9) thyroid: 2 cases (2.5%); 10) carcinoid: 1 case (1.2%); and 11) multiple myeloma: 1 case (1.2%). Divided by gender, for women, the main three sites were: breast, unknown, and ovary. For men, the main three sites were: lung, gastrointestinal, and testicular. Oldest cases were breast cancer (87 and 85 years); youngest cases were testicular (23 and 25 years). Solitary lesions were observed in 56 cases (71.7%); multiple lesions were observed in 22 cases (28.2%). Forty-two cases had a white or yellowish color, while 6 cases presented an orange color.Conclusion: Primary cancer sites and clinical features of choroidal metastasis in Mexican patients show important differences from other populations previously studied, mainly the presence of a higher proportion of gastrointestinal and renal cancer, as well as higher incidence of ovarian and testicular cancer. These types of cancer, although not as common as breast or lung, need to be taken into account when studying Mexican patients living abroad.Keywords: choroidal neoplasms, eye neoplasms, neoplasm metastasis, ovarian neoplasms, testicular neoplasms |
