Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks

Autor: Mart A.F.J. van de Laar, Inger L. Meek, Harald E. Vonkeman
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Pharmaceuticals, Vol 3, Iss 7, Pp 2146-2162 (2010)
Druh dokumentu: article
ISSN: 1424-8247
DOI: 10.3390/ph3072146
Popis: While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin.
Databáze: Directory of Open Access Journals