Pulmonary tuberculosis infection and CMV reactivation following daratumumab treatment in a patient with relapsed plasmablastic lymphoma
| Autor: | Wenyue Cao, Yuling Wan, Xingcheng Yang, Wei Huang, Jia Wei |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Blood Science, Vol 4, Iss 4, Pp 205-208 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2543-6368 00000000 |
| DOI: | 10.1097/BS9.0000000000000134 |
| Popis: | Plasmablastic lymphoma (PBL) is an aggressive lymphoma with limited treatment strategies. Tuberculosis (TB) infection poses a high risk for patients with hematologic malignancies, especially those treated with immune agents but were never reported post-daratumumab treatment. Herein, we reported a TB infection in a 57-year-old male diagnosed with HIV-negative PBL receiving daratumumab-based treatment, who showed atypical lung infection and yielded Mycobacterium tuberculosis and cytomegalovirus (CMV) in the bronchoalveolar lavage fluid. Anti-TB therapy was administered, and the following daratumumab treatment was complete with good tolerance. In this case, we demonstrated that TB infection might occur after daratumumab therapy, and adequate attention should be paid to atypical symptoms. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|