Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart

Autor: TyAnna L. Lovato, Richard M. Cripps
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Cardiovascular Development and Disease, Vol 3, Iss 2, p 18 (2016)
Druh dokumentu: article
ISSN: 2308-3425
DOI: 10.3390/jcdd3020018
Popis: The Drosophila cardiac tube was once thought to be a simple linear structure, however research over the past 15 years has revealed significant cellular and molecular complexity to this organ. Prior reviews have focused upon the gene regulatory networks responsible for the specification of the cardiac field and the activation of cardiac muscle structural genes. Here we focus upon highlighting the existence, function, and development of unique cell types within the dorsal vessel, and discuss their correspondence to analogous structures in the vertebrate heart.
Databáze: Directory of Open Access Journals