Autor: |
Shyh-Ren Chiang, Fang Jung, Hung-Jen Tang, Chung-Hua Chen, Chi-Chung Chen, Hsiu-Yin Chou, Yin-Ching Chuang |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
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Zdroj: |
Journal of Microbiology, Immunology and Infection, Vol 51, Iss 6, Pp 770-777 (2018) |
Druh dokumentu: |
article |
ISSN: |
1684-1182 |
DOI: |
10.1016/j.jmii.2017.02.003 |
Popis: |
Background/purpose: Globally, multidrug-resistant Acinetobacter baumannii (MDRAB) has emerged as an important pathogen in nosocomial outbreaks. This study aimed to investigate the correlation between the biofilm formation and survival of MDRABs, and to investigate the antiseptic efficacy of hand sanitizers for the MDRABs, embedded with biofilm (MDRAB-Bs). Methods: The MDRABs were selected randomly after pulsed-field gel electrophoresis (PFGE), and their biofilm formation was analyzed. Desiccation and ethanol tolerances were assayed to test the bacterial survival. The antiseptic efficacy of combined chlorhexidine gluconate (CHG) and 70% ethanol agents against MDRAB-Bs were compared with the 70% ethanol cleanser. Results: Eleven MDRABs, which varied in biofilm formation (MRDAB-B) and planktonic type (MDRAB-P), were tested. In desiccation survival, the mean survival time for the MDRAB-Bs was 49.0 days which was significantly higher than that of their planktonic type (17.3 days) (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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