Seizure induced by tranexamic acid in a patient with chronic kidney disease on maintenance dialysis

Autor: Kar Wah Fuah, Christopher T. S. Lim, Daniel C. L. Pang, Jin Shyan Wong
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Saudi Journal of Kidney Diseases and Transplantation, Vol 29, Iss 1, Pp 207-209 (2018)
Druh dokumentu: article
ISSN: 1319-2442
DOI: 10.4103/1319-2442.225177
Popis: Tranexamic acid (TXA) is an antifibrinolytic agent commonly used to achieve hemostasis. However, there have been a few case reports suggesting that high-dose intravenous TXA has epileptogenic property. In patients with renal impairment, even administering the usual recommended dose of TXA can induce seizure episodes. We present here a patient on hemodialysis who developed seizures after receiving two doses of TXA over 5 h period.
Databáze: Directory of Open Access Journals