| Autor: |
Giovanna Ribeiro Souto, Alessandro Oliveira de Jesus, Takeshi Kato Segundo, Paôlla Freitas Perdigão, Fernando de Oliveira Costa, Ricardo Alves de Mesquita |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Brazilian Journal of Oral Sciences, Vol 18 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1677-3225 |
| DOI: |
10.20396/bjos.v18i0.8656600 |
| Popis: |
Aim: The objective was to compare the density and degranulation of mast cells on specimens obtained from individuals diagnosed with gingivitis or chronic periodontitis who were either non-HIV-infected or HIV-infected patients treated with highly active antiretroviral therapy (HAART). Methods: Gingival samples were taken from 16 non-HIV-infected individuals and 17 HIV-infected individuals diagnosed with gingivitis and chronic periodontitis. The samples were processed and stained with 0.3 percent o-toluidine blue. Densities (cells/mm²) and percentages of intact and degranulated mast cells were obtained. Results: No statistically significant differences were observed in the mast cell density and the percentage of degranulated mast cells between non-HIV-infected and HIV-infected individuals diagnosed with gingivitis and chronic periodontitis. Mononuclear inflammatory infiltrate was weakly correlated with the percentage of mast cells degranulated for both groups. Conclusions: There are no differences of the density and degranulation of mast cells in gingival tissue between non-HIV-infected and HIV-infected patients undergoing HAART, both groups with diagnosis of gingivitis or chronic periodontitis. This may be a result of the recovery of the immunologic system by HAART treatment. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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