Data on proteomic analysis of milk extracellular vesicles from bovine leukemia virus-infected cattle

Autor: Md. Matiur Rahman, Yassien Badr, Yuji O. Kamatari, Yuko Kitamura, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Data in Brief, Vol 33, Iss , Pp 106510- (2020)
Druh dokumentu: article
ISSN: 2352-3409
DOI: 10.1016/j.dib.2020.106510
Popis: Milk extracellular vesicles (EVs) are nanoparticles that contain proteins, mRNAs, microRNAs, DNAs, and lipids that involved in several biological functions. Milk EVs provide proteins that could represent relevant novel biomarkers for monitoring of different diseases such as breast cancer and mastitis in humans and animals, respectively. Bovine leukemia virus (BLV) is an oncogenic virus that causes progressive B-cell lymphosarcoma in cattle. Here, we aimed to identify proteins in milk EVs from BLV-infected cattle compared with those from uninfcetd cattle. Proteomic analysis was performed by using a comprehensive nano liquid chromatography-tandem mass spectrometry (nanoLC-MS/MS) approach. Identified proteins were analyzed by using a proteomic software, Scaffold-Data Independent Acquisition (Scaffold-DIA).
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