Mortality and Disability According to Baseline Blood Pressure in Acute Ischemic Stroke Patients Treated by Thrombectomy: A Collaborative Pooled Analysis

Autor: Benjamin Maïer, Benjamin Gory, Guillaume Taylor, Julien Labreuche, Raphaël Blanc, Michael Obadia, Marie Abrivard, Stanislas Smajda, Jean‐Philippe Desilles, Hocine Redjem, Gabriele Ciccio, Anne Claire Lukaszewicz, Francis Turjman, Roberto Riva, Paul Emile Labeyrie, Alain Duhamel, Jacques Blacher, Michel Piotin, Bertrand Lapergue, Mikael Mazighi
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.117.006484
Popis: BackgroundHigh blood pressure (BP) is associated with worse clinical outcomes in the setting of acute ischemic stroke, but the optimal blood pressure target is still a matter of debate. We aimed to study the association between baseline BP and mortality in acute ischemic stroke patients treated by mechanical thrombectomy. Methods and ResultsA total of 1332 acute ischemic stroke patients treated by mechanical thrombectomy were enrolled (from January 2012 to June 2016) in the ETIS (Endovascular Treatment in Ischemic Stroke) registry. Linear and polynomial logistic regression models were used to assess the association between BP and mortality and functional outcome at 90 days. Highest mortality was found at lower and higher baseline systolic blood pressure (SBP) values following a J‐ or U‐shaped relationship, with a nadir at 157 mm Hg (95% confidence interval 143‐170). When SBP values were categorized in 10–mm Hg increments, the odds ratio for all‐cause mortality was 3.78 (95% confidence interval 1.50‐9.55) for SBP
Databáze: Directory of Open Access Journals