Detection of SNP effects on feed conversion ratio in pigs based on entropy approach

Autor: Henry Reyer, Klaus Wimmers, Patrick Varley, Tomasz Szwaczkowski, Alicja Borowska
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Acta Fytotechnica et Zootechnica, Vol 19, Iss 4, Pp 103-105 (2016)
Druh dokumentu: article
ISSN: 1335-258X
1336-9245
DOI: 10.15414/afz.2016.19.03.103-105
Popis: The objectives of the study were to classify SNPs according to their contribution to the feed conversion ratio and to indicate interactions between the most informative SNPs using entropy analysis. The records of 1296 pigs were included. Two selection criteria for molecular data were applied: call rate 0.95 and minor allele frequency 0.05. After this, 50 951 SNPs were included into the entropy analysis. For each SNP entropy and conditional entropy were estimated. For interaction analyses the most informative SNPs were selected. For each pair of SNPs, the mutual information was assessed. A majority of the loci studied showed relatively small contributions. The most informative SNPs are mainly located on chromosomes: 1, 4, 7, 9 and 14. Whereas important interactions between SNP pairs were detected on chromosomes: 1, 14, 15 and 16. High mutual information was registered for SNPs located nearby.
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