| Autor: |
SHI Jia-jia*, ZHU Guo-zhen |
| Jazyk: |
čínština |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Zhongguo linchuang yanjiu, Vol 36, Iss 2, Pp 266-270 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1674-8182 |
| DOI: |
10.13429/j.cnki.cjcr.2023.02.022 |
| Popis: |
Objective To investigate the value of urinary neutrophil gelatinase-associated lipocalin (NGAL) in the early diagnosis of IgA nephropathy and its relationship with the cumulative survival rate of kidney in patients with IgA nephropathy. Methods The case group consisted of 39 patients with primary IgA nephropathy diagnosed by renal biopsy in the Second Hospital of Shanxi Medical University from March 2017 to July 2018, and the control group consisted of 55 healthy people in the same period. Patients with IgA nephropathy were divided into mild, moderate and severe groups according to the proportion of renal tubulointerstitial injury area, and into high and low urinary NGAL groups according to the median urine NGAL. The levels of urinary NGAL in each group were compared. To analyze the early diagnostic efficacy of urine NGAL and urine kidney injury molecule-1 (KIM-1) for IgA nephropathy. The correlation between urinary NGAL and various clinical indicators was analyzed. The cumulative survival rate of the kidney was compared among groups with different urinary NGAL levels and groups with different degrees of tubulointerstitial injury. Results There were statistically significant differences in urinary NGAL levels between the case group and the control group, as well as between groups with different degrees of tubulointerstitial injury (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
