Normal skin of HIV-infected individuals contains increased numbers of dermal CD8 T cells and normal numbers of Langerhans cells

Autor:	M.C.G. Galhardo, F.F. Alvarenga, G. Schueler, M. Perez, M.G. Morgado, H. Ferreira, L.M.S. Azevedo, E.P. Sampaio, E.N. Sarno
Jazyk:	angličtina
Rok vydání:	2004
Předmět:	HIV Skin immune system CD8 T cells CD4-CD8 ratio Langerhans cells Medicine (General) R5-920 Biology (General) QH301-705.5
Zdroj:	Brazilian Journal of Medical and Biological Research, Vol 37, Iss 5, Pp 745-753 (2004)
Druh dokumentu:	article
ISSN:	0100-879X 1414-431X
DOI:	10.1590/S0100-879X2004000500017
Popis:	Dysregulation of the skin immune system (SIS) could explain the high prevalence of skin disorders in HIV+ individuals. The present study was carried out to determine whether alterations in the cell population of SIS and epidermal immunoactivation occur in the normal skin of HIV+ individuals. Forty-five biopsies were taken from the normal upper arm skin of 45 HIV+ patients and of 15 healthy controls. HIV+ individuals were divided into three categories according to their CD4 cell blood count (
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/6e3467b5b660434db8218443851e12c7 Zobrazit plný text záznamu View record in DOAJ