| Autor: |
Abdulkareem Adam Olaitan, Babamale Abdulkareem Olarewaju, Anifowoshe Abass Toba, Opeyemi Olufunke Adenike Opeyemi Olufunke Adenike, Oloriegbe Nusirat, Adamolekun Comfort, Adetula Samson, Ala Adeola Adefoluke |
| Jazyk: |
English<br />Serbian |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Bulletin of Natural Sciences Research, Vol 12, Iss 2, Pp 1-6 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2738-1013 |
| DOI: |
10.5937/bnsr12-35454 |
| Popis: |
Increasing drug resistance is a great threat to malaria control. Therefore, a continuous investigation into alternative therapy to mitigate malaria-associated damages is important. In this study, we investigated the anti-hypoglycaemic and anti-hyperlipidaemic effects of aqueous extract of Morinda lucida leaf in Plasmodium berghei-infected mice. Twenty-five mice were randomly grouped into five: Uninfected, infected-untreated, chloroquine (20 mg/kg, per oral), and extract-treated (400 mg/kg and 800 mg/kg, respectively, per oral) groups. Fasting blood glucose was measured before parasite inoculation and after the last treatment. Blood was collected for lipid profile assay at the end of the 4-day treatment. Our results revealed that both chloroquine and the extract lowered parasite growth (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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