Population genomic evidence of a putative ‘far-west’ African cryptic taxon in the Anopheles gambiae complex

Autor: Beniamino Caputo, Carlo M. De Marco, Verena Pichler, Giordano Bottà, Kelly L. Bennett, Alfred Amambua-Ngwa, Sessinou B. Assogba, Kevin O. Opondo, Chris S. Clarkson, Jacob A. Tennessen, David Weetman, Alistair Miles, Alessandra della Torre
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-024-06809-y
Popis: Abstract The two main Afrotropical malaria vectors - Anopheles coluzzii and An. gambiae – are genetically distinct and reproductively isolated across West Africa. However, populations at the western extreme of their range are assigned as “intermediate” between the two species by whole genome sequence (WGS) data, and as hybrid forms by conventional molecular diagnostics. By exploiting WGS data from 1190 specimens collected across west Africa via the Anopheles gambiae 1000 Genomes network, we identified a putative taxon in the far-west (provisionally named Bissau molecular form), which did not arise by admixture but rather may have originated at the same time as the split between An. coluzzii and An. gambiae. Intriguingly, this taxon lacks insecticide resistance mechanisms commonly observed in the two main species. These findings lead to a change of perspective on malaria vector species in the far-west region with potential for epidemiological implications, and a new challenge for genetic-based mosquito control approaches.
Databáze: Directory of Open Access Journals
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