Hemodynamic, Oxygenation and Lymphocyte Parameters Predict COVID-19 Mortality

Autor: Choirina Windradi, Tri Pudy Asmarawati, Alfian Nur Rosyid, Erika Marfiani, Bagus Aulia Mahdi, Okla Sekar Martani, Giarena Giarena, Esthiningrum Dewi Agustin, Milanitalia Gadys Rosandy
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Pathophysiology, Vol 30, Iss 3, Pp 314-326 (2023)
Druh dokumentu: article
ISSN: 1873-149X
DOI: 10.3390/pathophysiology30030025
Popis: The mortality of COVID-19 patients has left the world devastated. Many scoring systems have been developed to predict the mortality of COVID-19 patients, but several scoring components cannot be carried out in limited health facilities. Herein, the authors attempted to create a new and easy scoring system involving mean arterial pressure (MAP), PF Ratio, or SF ratio-respiration rate (SF Ratio-R), and lymphocyte absolute, which were abbreviated as MPL or MSLR functioning, as a predictive scoring system for mortality within 30 days for COVID-19 patients. Of 132 patients with COVID-19 hospitalized between March and November 2021, we followed up on 96 patients. We present bivariate and multivariate analyses as well as the area under the curve (AUC) and Kaplan–Meier charts. From 96 patients, we obtained an MPL score of 3 points: MAP < 75 mmHg, PF Ratio < 200, and lymphocyte absolute < 1500/µL, whereas the MSLR score was 6 points: MAP < 75 mmHg, SF Ratio < 200, lymphocyte absolute < 1500/µL, and respiration rate 24/min. The MPL cut-off point is 2, while the MSLR is 4. MPL and MSLR have the same sensitivity (79.1%) and specificity (75.5%). The AUC value of MPL vs. MSLR was 0.802 vs. 0.807. The MPL ≥ 2 and MSLR ≥ 4 revealed similar predictions for survival within 30 days (p < 0.05). Conclusion: MPL and MSLR scores are potential predictors of mortality in COVID-19 patients within 30 days in a resource-limited country.
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