Cancer treatment in determination of hearing loss

Autor: Priscila Feliciano de Oliveira, Camila Silva Oliveira, Joice Santos Andrade, Tamara Figueiredo do Carmo Santos, Aline Cabral de Oliveira-Barreto
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Brazilian Journal of Otorhinolaryngology, Vol 82, Iss 1, Pp 65-69 (2016)
Druh dokumentu: article
ISSN: 1808-8686
DOI: 10.1016/j.bjorl.2014.12.010
Popis: ABSTRACT INTRODUCTION: Chemotherapy and radiotherapy in oncology have repercussions in hearing health, and can damage structures of the inner ear. These repercussions usually, result in a bilateral and irreversible hearing loss. OBJECTIVE: To identify sensorineural hearing loss cases with complaints of tinnitus and difficulty in speech understanding and investigate their relationship with the types of chemotherapy and radiotherapy the patients received. METHODS: Cross-sectional, clinical, observational, analytical, historical cohort study of 58 subjects treated in a public hospital in the state of Sergipe, diagnosed with neoplasia. The subjects were submitted to anamnesis, conventional pure tone audiometry, and speech recognition threshold. RESULTS: Of the 116 ears, 25.9% presented sensorioneural hearing loss characterized by changes in high frequencies. There was a positive correlation between hearing loss and the association of chemotherapy and radiotherapy ( p = 0.035; R = 0.196). The auditory complaint analysis shows that most of the subjects had tinnitus and speech understanding difficulty, even with a normal auditory threshold. CONCLUSIONS: Cancer treatment causes hearing loss, associated with the administration of chemotherapy and radiotherapy. Cyclophosphamide increased the risk of causing hearing loss. Complaints of tinnitus and speech understanding difficulty were observed.
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