Optimization of contrast medium volume for abdominal CT in oncologic patients: prospective comparison between fixed and lean body weight-adapted dosing protocols

Autor: Damiano Caruso, Elisa Rosati, Nicola Panvini, Marco Rengo, Davide Bellini, Giulia Moltoni, Benedetta Bracci, Elena Lucertini, Marta Zerunian, Michela Polici, Domenico De Santis, Elsa Iannicelli, Paolo Anibaldi, Iacopo Carbone, Andrea Laghi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Insights into Imaging, Vol 12, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 1869-4101
DOI: 10.1186/s13244-021-00980-0
Popis: Abstract Background Patient body size represents the main determinant of parenchymal enhancement and by adjusting the contrast media (CM) dose to patient weight may be a more appropriate approach to avoid a patient over dosage of CM. To compare the performance of fixed-dose and lean body weight (LBW)-adapted contrast media dosing protocols, in terms of image quality and parenchymal enhancement. Results One-hundred cancer patients undergoing multiphasic abdominal CT were prospectively enrolled in this multicentric study and randomly divided in two groups: patients in fixed-dose group (n = 50) received 120 mL of CM while in LBW group (n = 50) the amount of CM was computed according to the patient’s LBW. LBW protocol group received a significantly lower amount of CM (103.47 ± 17.65 mL vs. 120.00 ± 0.00 mL, p
Databáze: Directory of Open Access Journals
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