Late HIV Diagnosis but Earlier Antiretroviral Treatment Initiation in Northwest Spain: Impact of Current Treatment Guidelines

Autor: Purificación Cid-Silva, Luis Margusino-Framiñán, Vanesa Balboa-Barreiro, Berta Pernas-Souto PhD, Álvaro Mena-De-Cea PhD, Isabel Martín-Herranz, Ángeles Castro-Iglesias PhD, Eva Poveda PhD
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of the International Association of Providers of AIDS Care, Vol 18 (2019)
Druh dokumentu: article
ISSN: 2325-9582
23259582
DOI: 10.1177/2325958218821940
Popis: Background: Current HIV treatment guidelines recommend antiretroviral treatment (ART) initiation for all HIV-infected individuals regardless of CD4 count. This study evaluates the immunological and virological status and the clinical characteristics of patients who have started ART in the last 8 years in the Northwest of Spain. Methods: All HIV-infected patients who have started ART between January 2009 and December 2016 at a reference hospital in the Northwest of Spain were included in this retrospective observational study. Epidemiological, clinical, and immunovirological features and antiretroviral drugs used for initiation were recorded. A statistical analysis was performed using SPSS version 19 software. Categorical and continuous variables were compared by the specific statistical tests, and a logistic regression model was used to identify time associated with Center for Disease Control and Prevention (CDC) categories change. Results: A high proportion of HIV-infected patients (66.7%) had initiated ART with CD4 counts
Databáze: Directory of Open Access Journals