| Autor: |
Tomas Kovarnik, Matsuo Hitoshi, Ales Kral, Stepan Jerabek, David Zemanek, Yoshiaki Kawase, Hiroyuki Omori, Toru Tanigaki, Jan Pudil, Alexandra Vodzinska, Marian Branny, Roman Stipal, Petr Kala, Jan Mrozek, Martin Porzer, Tomas Grezl, Kamil Novobilsky, Oscar Mendiz, Karel Kopriva, Martin Mates, Martin Chval, Zhi Chen, Pavel Martasek, Ales Linhart |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 9 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2047-9980 |
| DOI: |
10.1161/JAHA.121.021490 |
| Popis: |
Background The FiGARO (FFR versus iFR in Assessment of Hemodynamic Lesion Significance, and an Explanation of Their Discrepancies) trial is a prospective registry searching for predictors of fractional flow reserve/instantaneous wave‐free ratio (FFR/iFR) discrepancy. Methods and Results FFR/iFR were analyzed using a Verrata wire, and coronary flow reserve was analyzed using a Combomap machine (both Philips‐Volcano). The risk polymorphisms for endothelial nitric oxide synthase and for heme oxygenase‐1 were analyzed. In total, 1884 FFR/iFR measurements from 1564 patients were included. The FFR/iFR discrepancy occurred in 393 measurements (20.9%): FFRp (positive)/iFRn (negative) type (264 lesions, 14.0%) and FFRn/iFRp (129 lesions, 6.8%) type. Coronary flow reserve was measured in 343 lesions, correlating better with iFR (R=0.56, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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