Peppermint Oil Decreases the Production of Virulence-Associated Exoproteins by Staphylococcus aureus

Autor: Xu-Ming Deng, Wen-Zhi Ren, Bing-Feng Leng, Ming-Jing Luo, Hong-En Li, Jian-Feng Wang, Jing Dong, Jia-Zhang Qiu, Jing Li
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Molecules, Vol 16, Iss 2, Pp 1642-1654 (2011)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules16021642
Popis: The present study aimed to evaluate the antimicrobial activity of peppermint oil against Staphylococcus aureus, and further investigate the influence of peppermint oil on S. aureus virulence-related exoprotein production. The data show that peppermint oil, which contained high contents of menthone, isomenthone, neomenthol, menthol, and menthyl acetate, was active against S. aureus with minimal inhibitory concentrations (MICs) ranging from 64-256 µg/mL, and the production of S. aureus exotoxins was decreased by subinhibitory concentrations of peppermint oil in a dose-dependent manner. The findings suggest that peppermint oil may potentially be used to aid in the treatment of S. aureus infections.
Databáze: Directory of Open Access Journals