| Autor: |
Farheen Danish, Hira Salam, Muhammad Asif Qureshi, Mughal Nouman |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Interdisciplinary Neurosurgery, Vol 25, Iss , Pp 101239- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2214-7519 |
| DOI: |
10.1016/j.inat.2021.101239 |
| Popis: |
Introduction: Brain tumors encompass a broad group showing wide geographic and ethnic variation in incidence. In keeping view the critical dearth of epidemiological data on brain tumors from Pakistan we undertook this study, with the aim to first describe spectrum of brain tumors at our center, and then to compare our results with prevalence pattern in global population using TCGA clinical dataset. Material and methods: Data was retrospectively collected from Histopathology archives of Dow Diagnostic Reference and Research Lab (DDRRL), Dow University of Health Sciences (DUHS), Pakistan. Clinical data set for Low Grade Gliomas (LGG) and Glioblastoma (GBM) cohort (TCGA) was downloaded from cbioportal (www.cbioportal.org). All the analyses were performed in IBM SPSS v. 24 and P value < 0.05 was set as threshold to show significant difference. Results: Total 430 cases were enrolled in our study comprising of 224 males and 206 females of which 132 (30.7%) cases were of diffuse gliomas. WHO grade I (53.6%) was the prevalent grade group with nearly half (49.3%) cases diagnosed in adults (>36 years). Significant difference was recorded between our centre and global dataset with respect to age (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
