Infections in children with simple obesity: The relation to phagocytic function and serum leptin

Autor: Nadin N. Toaima, Rasha H. El-Owaidy, Dina L. Zaki, Lerine B. Eldin
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Infection and Public Health, Vol 12, Iss 1, Pp 57-61 (2019)
Druh dokumentu: article
ISSN: 1876-0341
DOI: 10.1016/j.jiph.2018.08.007
Popis: Introduction: There is a possible association between obesity and infections. We sought to investigate phagocytic functions in obese children and their relation to serum leptin levels. Methods: A cross sectional, controlled study was conducted, comprising 40 cases with simple visceral-type obesity. Subjects were evaluated for percentage of caloric intake, frequency and type of infections, body mass index (BMI) z score, in addition to complete blood counting, serum leptin assay (ELISA) and Dihydrorhodamine (DHR) flowcytometry. Results: Cases were 21 males (52.5%) and 19 females (47.5%) with mean age 7.14 years ± 2.73 SD with median duration of obesity 4.2 years (IQR: 2–6). Cases had higher frequency of infections compared with controls (p
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