Association between serum inflammatory biomarkers and atrial low voltage in patients with atrial fibrillation: A phase 1 FIB-MARK study

Autor: Tetsuma Kawaji, Koh Ono, Naoya Sowa, Takanori Aizawa, Shun Hojo, Hidenori Yaku, Kenji Nakatsuma, Kazuhisa Kaneda, Masashi Kato, Takafumi Yokomatsu, Satoshi Shizuta, Shinji Miki, Takeshi Kimura
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Cardiology: Heart & Vasculature, Vol 37, Iss , Pp 100904- (2021)
Druh dokumentu: article
ISSN: 2352-9067
DOI: 10.1016/j.ijcha.2021.100904
Popis: Background: The mechanisms leading to atrial fibrosis in patients with atrial fibrillation (AF), especially in relation to inflammation, remain unclear. Methods and Results: Forty biomarkers were measured in peripheral blood samples collected prior to catheter ablation, and the association with left atrial (LVZ) was evaluated in 16 consecutive patients. The median %LVZ was 17%. In Pearson’s correlation analysis, interleukin(IL)-17A and interferon(IFN)-γ showed the most significant positive and negative correlations with %LVZ (R = 0.35 and 0.43, P
Databáze: Directory of Open Access Journals