Expressions of sFRP1 and β-catenin in cervical cancer

Autor:	Zhang Xiao-Yan, Wang Lin, Qiao Yuhuan, Guo Ruixia
Jazyk:	angličtina
Rok vydání:	2012
Předmět:	cervical cancer secreted frizzled-related protein1 β-catenin immunohistochemistry prognosis Biochemistry QD415-436
Zdroj:	Journal of Medical Biochemistry, Vol 31, Iss 1, Pp 6-11 (2012)
Druh dokumentu:	article
ISSN:	1452-8258 1452-8266
Popis:	This study aimed to investigate the expressions of secreted frizzled-related protein 1 (sFRP1) and β-catenin in cervical cancer and cervical intraepithelial neoplasia (CIN), and to explore the relationship between both proteins and the prognosis of cervical cancer. Immunohistochemistry was performed to detect the protein expressions of sFRP1 and β-catenin in cervical cancer (n=78), CIN (n=30) and normal cervical tissues (n=20), and the relationships of sFRP1 and β-catenin with the clinicopathological characteristics and prognosis of cervical cancer were analyzed. The positive rate of sFRP1 was 100%, 70% and 33.3% in the normal cervical tissues, CIN and cervical cancer, respectively (P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/6d8fd132609845a5b588a9d6859e6634 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF