The effect of synbiotic tablet usage on the clinical and biochemical parameters in smokers and nonsmokers with gingivitis: a randomized placebo-controlled clinical trial

Autor: Nuray Ercan, Ebru Olgun, Üçler Kisa, Mehmet Yalim
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Tobacco Induced Diseases, Vol 16, Iss 3 (2018)
Druh dokumentu: article
ISSN: 1617-9625
DOI: 10.18332/tid/94756
Popis: Introduction The aim of this study is to evaluate the efficacy of oral administration of synbiotic tablets on the clinical parameters and the levels of selected inflammatory mediators in gingival crevicular fluid (GCF) in smokers and non-smokers with gingivitis. Methods Eighty patients with gingivitis (40 smoker (+), 40 non-smoker (-)), randomly assigned to test (T) or control (C) groups. Each subject was instructed to chew one tablet per day, during 30 days. Clinical parameters including plaque and gingival indices and GCF samples obtained from all subjects on baseline, 1st month, and 2nd month. The GCF levels of interleukin (IL)-6, IL-8 and IL-10 were determined. Results All clinical and biochemical parameters for all groups were significantly reduced compared to baseline (p
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