The Nonlinear Relationship Between Temperature and Prognosis in Sepsis-induced Coagulopathy Patients: A Retrospective Cohort Study from MIMIC-IV Database

Autor: Guojun Chen, Tianen Zhou, Jingtao Xu, Qiaohua Hu, Jun Jiang, Weigan Xu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Western Journal of Emergency Medicine, Vol 25, Iss 5, Pp 697-707 (2024)
Druh dokumentu: article
ISSN: 1936-900X
1936-9018
DOI: 10.5811/westjem.18589
Popis: Background: The prognostic value of body temperature in sepsis-induced coagulopathy (SIC) remains unclear. In this study we aimed to investigate the association between temperature and mortality among SIC patients. Methods: We analyzed data for 9,860 SIC patients from an intensive care database. Patients were categorized by maximum temperature in the first 24 hours into the following: ≤36.0°C; 36.0–37.0°C; 37.0–38.0°C; 38.0–39.0°C; and ≥39.0°C. The primary outcome was 28-day mortality. We used multivariate regression to analyze the temperature-mortality association. Results: The 37.0–38.0°C, 38.0–39.0°C and ≥39.0°C groups correlated with lower 28-day mortality (adjusted HR 0.70, 0.76 and 0.72, respectively), while the
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