Small vessel occlusion and syphilis in patients with first-ever ischemic stroke
| Autor: | Matheus Gomes Ferreira, Valeria Cristina Scavasine, Giovanni Luís Breda, Bernardo Montesanti Machado de Almeida, Viviane de Hiroki Flumignan Zétola, Marcos Christiano Lange |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Arquivos de Neuro-Psiquiatria, Vol 79, Iss 2, Pp 103-106 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1678-4227 0004-282x |
| DOI: | 10.1590/0004-282x-anp-2020-0178 |
| Popis: | ABSTRACT Background: Syphilis is an endemic disease, particularly in low- and middle-income countries, with vascular involvement in large vessels (aortitis), but no clear relationship with stroke patients, except for those who presented with meningovascular neurosyphilis. Objective: To investigate the relationship between a positive history of syphilis determined by serological testing and ischemic stroke etiology, particularly small vessel disease (SVD). Methods: In total, 269 first-ever ischemic stroke patients admitted to the stroke unit were tested for syphilis. Patients with neurosyphilis were excluded. All patients were classified according to the ASCOD phenotyping as SVD — when SVD was the potential causal mechanism (S1) — or non-SVD — when SVD was uncertain (S2), unlike (S3), or not detected (S0). Results: Syphilis was positive in 32 (12%) patients. When comparing patients with positive and negative serology, the only significant difference was SVD as the causal mechanism (S1) in patients with positive results: 9 (28%) vs. 22 (9%), p |
| Databáze: | Directory of Open Access Journals |
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