Meta-analysis of the role of neutrophil to lymphocyte ratio in neonatal sepsis

Autor:	Jingyang Chen, Sanaz Yasrebinia, Arshin Ghaedi, Monireh Khanzadeh, Stephan Quintin, Abeer Dagra, Rodeania Peart, Brandon Lucke-Wold, Shokoufeh Khanzadeh
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Neutrophil to lymphocyte ratio Neonatal sepsis Systematic review Meta-analysis Infectious and parasitic diseases RC109-216
Zdroj:	BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-13 (2023)
Druh dokumentu:	article
ISSN:	1471-2334
DOI:	10.1186/s12879-023-08800-0
Popis:	Abstract Introduction The neutrophil to lymphocyte ratio (NLR), an inflammatory biomarker, measures innate-adaptive immune system balance. In this systematic review and meta-analysis, we aim to analyze the current literature to evaluate the diagnostic role of NLR in neonatal sepsis. Methods PubMed, Web of Science, and Scopus were used to conduct a systematic search for relevant publications published before May 14, 2022. Results Thirty studies, including 2328 neonates with sepsis and 1800 neonates in the control group, were included in our meta-analysis. The results indicated that NLR is higher in neonates with sepsis compared to healthy controls (SMD = 1.81, 95% CI = 1.14–2.48, P-value
Databáze:	Directory of Open Access Journals
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