BCR/ABL positive thrombocythemia: a diagnostic dilemma

Autor: Lubna Zafar, Feroz Alam, Anjum Parvez, Srikant Behera
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: The Egyptian Journal of Internal Medicine, Vol 29, Iss 2, Pp 83-85 (2017)
Druh dokumentu: article
ISSN: 1110-7782
2090-9098
DOI: 10.4103/ejim.ejim_21_16
Popis: Both chronic myeloid leukemia and essential thrombocythemia are part of the spectrum of myeloproliferative neoplasm. Therefore, considerable overlap may occur in the clinical manifestations, and hematological and molecular findings in some patients. We report here a case of a 45-year-old men who presented with thrombocytosis. Bone marrow aspiration yielded small megakaryocytes with hypolobulated nuclei and positive BCR-ABL rearrangement. A diagnosis of BCR-ABL+ essential thrombocythemia was made and imatinib was advised.
Databáze: Directory of Open Access Journals
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