New Keratoconus Risk Factors: A Cross-Sectional Case—Control Study

Autor: Eloi Debourdeau, Gabriel Planells, Chloe Chamard, David Touboul, Max Villain, Pascal Demoly, Fanny Babeau, Pierre Fournie, Vincent Daien
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Ophthalmology, Vol 2022 (2022)
Druh dokumentu: article
ISSN: 2090-0058
DOI: 10.1155/2022/6605771
Popis: Purpose. To evaluate risk factors associated with keratoconus in a monocentric cross-sectional case-control study. Methods. This observational study occurred from June 2019 to February 2021 in a university hospital (France). The case group consisted of 195 patients with keratoconus in at least one eye who were followed up by a corneal specialist. The control group consisted of 195 patients without any evidence of keratoconus on slit-lamp examination and corneal topography, who were matched 1 : 1 to controls by age and sex. Data were collected by a self-completed paper questionnaire before the consultation, and a multivariate logistic regression was performed. Results. Multivariate analysis revealed significant associations of keratoconus with family history (odds ratio [OR] = 22.2, p
Databáze: Directory of Open Access Journals
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