Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B.

Autor: Gloria Morizot, Romain Jouffroy, Albert Faye, Paul Chabert, Katia Belhouari, Ruxandra Calin, Caroline Charlier, Patrick Miailhes, Jean-Yves Siriez, Oussama Mouri, Hélène Yera, Jacques Gilquin, Roland Tubiana, Fanny Lanternier, Marie-France Mamzer, Christophe Legendre, Dominique Peyramond, Eric Caumes, Olivier Lortholary, Pierre Buffet
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: PLoS Neglected Tropical Diseases, Vol 10, Iss 1, p e0004304 (2016)
Druh dokumentu: article
ISSN: 1935-2727
1935-2735
DOI: 10.1371/journal.pntd.0004304
Popis: We report on 4 patients (1 immunocompetent, 3 immunosuppressed) in whom visceral leishmaniasis had become unresponsive to (or had relapsed after) treatment with appropriate doses of liposomal amphotericin B. Under close follow-up, full courses of pentavalent antimony were administered without life-threatening adverse events and resulted in rapid and sustained clinical and parasitological cure.
Databáze: Directory of Open Access Journals