Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B.
Autor: | Gloria Morizot, Romain Jouffroy, Albert Faye, Paul Chabert, Katia Belhouari, Ruxandra Calin, Caroline Charlier, Patrick Miailhes, Jean-Yves Siriez, Oussama Mouri, Hélène Yera, Jacques Gilquin, Roland Tubiana, Fanny Lanternier, Marie-France Mamzer, Christophe Legendre, Dominique Peyramond, Eric Caumes, Olivier Lortholary, Pierre Buffet |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: | |
Zdroj: | PLoS Neglected Tropical Diseases, Vol 10, Iss 1, p e0004304 (2016) |
Druh dokumentu: | article |
ISSN: | 1935-2727 1935-2735 |
DOI: | 10.1371/journal.pntd.0004304 |
Popis: | We report on 4 patients (1 immunocompetent, 3 immunosuppressed) in whom visceral leishmaniasis had become unresponsive to (or had relapsed after) treatment with appropriate doses of liposomal amphotericin B. Under close follow-up, full courses of pentavalent antimony were administered without life-threatening adverse events and resulted in rapid and sustained clinical and parasitological cure. |
Databáze: | Directory of Open Access Journals |
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