Correlation between the size of pheochromocytoma and the level of metanephrines

Autor: Rezkallah Emad, Elsaify Andrew, Hanna Ragai, Elsaify Wael
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Endocrine Regulations, Vol 57, Iss 1, Pp 183-190 (2023)
Druh dokumentu: article
ISSN: 1336-0329
DOI: 10.2478/enr-2023-0022
Popis: Objective. Pheochromocytomas (PHEO) and paraganglioma (PGLs) are rare neuroendocrine catecholamine-producing tumors that arise from the chromaffin cells of either the adrenal medulla or extra-adrenal paraganglionic tissues. Despite the recent advances in imaging technologies, biochemical evidence of excessive catecholamine production by the tumor is considered the most important test for the diagnosis of these tumors. The aim of the present study is to investigate the role of the catecholamine metabolites (normetanephrine and metanephrine) levels in the diagnosis of PHEO/PGLs and to evaluate if their levels correlate with the size of these tumors.
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