Autor: |
Janet Adede Carboo, Robin Claire Dolman-Macleod, Mary A. Uyoga, Arista Nienaber, Martani Johanni Lombard, Linda Malan |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Human Nutrition & Metabolism, Vol 34, Iss , Pp 200224- (2023) |
Druh dokumentu: |
article |
ISSN: |
2666-1497 |
DOI: |
10.1016/j.hnm.2023.200224 |
Popis: |
Background: Vitamin D (vitD) plays a role in iron metabolism by the suppression of hepcidin, while iron deficiency also impairs vitD metabolism. In undernourished children, iron and vitamin D deficiency are common. There is little knowledge of the inter-relationship between these two nutrients in undernourished and non-undernourished children. Aim: To assess the association between 25-hydroxyvitamin D (25(OH)D) and iron status, and the effect of 3 doses of 50,000 IU of vitD on iron status in undernourished and non-undernourished children. Methods: We measured serum 25(OH)D, haemoglobin (Hb), ferritin and soluble transferrin receptor in 121 undernourished and 51 non-undernourished children in clinics in the North-West Province of South Africa. Three doses of 50,000 IU/week of vitD was supplemented to children with suboptimal vitD levels. Results: The overall prevalence of suboptimal vitD concentration (25(OH)D |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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