| Autor: |
Pinpin Long, Jiahui Si, Ziwei Zhu, Yi Jiang, Yufei Wang, Qin Jiang, Wending Li, Xuedan Xu, Yutong You, Minghan Qu, Huihui Wang, Tingting Mo, Kang Liu, Jing Jiang, Qiuhong Wang, Canqing Yu, Yu Guo, Iona Y. Millwood, Robin G. Walters, Ximiao He, Yu Yuan, Hao Wang, Xiaomin Zhang, Meian He, Huan Guo, Zhengming Chen, Liming Li, Jun Lv, Chaolong Wang, Tangchun Wu |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-024-51751-6 |
| Popis: |
Abstract DNA methylation (DNAm) has been implicated in acute coronary syndrome (ACS), but the causality remains unclear in cross-sectional studies. Here, we conduct a prospective epigenome-wide association study of incident ACS in two Chinese cohorts (discovery: 751 nested case-control pairs; replication: 476 nested case-control pairs). We identified and validated 26 differentially methylated positions (DMPs, false discovery rate [FDR] |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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