Evaluation of rat plasma proteins after bothropic venom inoculation and treatment with Mesenquimal stem cells
| Autor: | Thalita Costa Telles, Ana Flávia Ribeiro Machado Michel, Maria Lúcia, Bruno Martins Melo, Adriane Costa-Val Pimenta Bicalho, Natália Melo Ocarino, Marilia Martins Melo |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Brazilian Archives of Biology and Technology, Vol 57, Iss 1, Pp 29-36 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1678-4324 1516-8913 |
| DOI: | 10.1590/S1516-89132014000100005 |
| Popis: | The aim of this work was to evaluate the mesenchymal stem cells treatment of rats with myonecrosis caused by Rhinocerophis alternatus venom through acute phase proteins (APP) profile. The animals were distributed into three experimental groups (G1, G2 and G3). G1 and G2 were inoculated with 120 μg of R. alternatus venom diluted in 200 µL of ultra-pure water in gastrocnemic muscle, while G3 received 200 µL of ultra-pure water. Three days after, G1 was treated with 5 X 10(6) MSC diluted in PBS and G2 and G3 only with PBS. Each three days after the treatments (3rd, 6th, 9th, 12th 15th days), blood of five animals in each group was collected in order to evaluate the APP. A decrease (P |
| Databáze: | Directory of Open Access Journals |
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