Temperature Interference on ZIKV and CHIKV Cycles in Mosquitoes and Mammalian Cells

Autor: Tiago Souza Salles, Erica Santos Martins-Duarte, Marcelo Damião Ferreira de Meneses, Monica Ferreira Moreira, Davis Fernandes Ferreira, Renata Campos Azevedo, Wanderley De Souza, Lucio Ayres Caldas
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Pathogens, Vol 13, Iss 9, p 814 (2024)
Druh dokumentu: article
ISSN: 2076-0817
DOI: 10.3390/pathogens13090814
Popis: Temperature is a determining factor for the viral cycle. In this study, we investigate the effect of different temperatures on the cycles of two important arboviruses—Zika (ZIKV) and Chikungunya (CHIKV)—in Vero (mammalian) and C6/36 (mosquito) cells. We compare genome quantification to infectivity at 28 °C and 37 °C in both cell types. Virus–cell interaction was also examined by transmission electron microscopy, allowing the observation of phenomena such as virus-surfing and giant forms for CHIKV, as well as the the scarcity of ZIKV in C6/36 cells compared to its cycle in mammalian cells.
Databáze: Directory of Open Access Journals