Pneumocystis pneumonia diagnosed by repeated measurements of β-D-glucan levels

Autor: Yasutaka Kawasaki, Akito Kozaneyori, Takuya Suda, Kohei Yamamoto, Daichi Kuwahara, Takatoshi Yoshio, Hiroaki Shintaku, Hiroshi Matsumoto
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 45, Iss , Pp 101905- (2023)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2023.101905
Popis: β-D-glucan is extensively employed as a supplementary diagnostic tool for Pneumocystis pneumonia (PCP) and typically yields positive results in most cases.We present a case of a 73-year-old woman with a history of rheumatoid arthritis, who was receiving biological agents and was admitted due to pneumonia.Initially, the β-D-glucan test was negative. However, as the disease progressed, it eventually turned positive, leading to the diagnosis of PCP. The patient was treated with corticosteroids and trimethoprim-sulfamethoxazole, resulting in pneumonia resolution.Our findings suggest that repeated assessment of β-D-glucan levels holds diagnostic value in patients without human immunodeficiency virus infection.
Databáze: Directory of Open Access Journals