| Autor: |
Justin Xavier Moore, Sydney Elizabeth Andrzejak, Malcolm S. Bevel, Samantha R. Jones, Martha S. Tingen |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
SSM: Population Health, Vol 19, Iss , Pp 101185- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2352-8273 |
| DOI: |
10.1016/j.ssmph.2022.101185 |
| Popis: |
Background: Several studies suggest that chronic stress may be associated with increased risk of cancer mortality. Our study sought to determine the association between allostatic load (AL), a measure of cumulative stress, and risk of cancer death; and whether these associations varied by race/ethnicity. Methods: We performed retrospective analysis using National Health and Nutrition Examination Survey (NHANES) years 1988 through 2010 linked with the National Death Index through December 31, 2019. We fit Fine & Gray Cox proportional hazards models to estimate sub-distribution hazard ratios (SHRs) of cancer death between high and low AL status (models adjusted for age, sociodemographics, and comorbidities). Results: In fully adjusted models, high AL was associated with a 14% increased risk of cancer death (adjusted (SHR): 1.14, 95% CI: 1.04–1.26) among all participants and a 18% increased risk of cancer death (SHR:1.18, 95% CI: 1.03–1.34) among Non-Hispanic White (NH-White) adults. When further stratified by age (participants aged |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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