Effect of Folic Acid Intake on Infant and Child Allergic Diseases: Systematic Review and Meta-Analysis

Autor: Zekun Chen, Yan Xing, Xue Yu, Yuqi Dou, Defu Ma
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Frontiers in Pediatrics, Vol 8 (2021)
Druh dokumentu: article
ISSN: 2296-2360
DOI: 10.3389/fped.2020.615406
Popis: Objective: This study aimed to analyze the effect of folic acid supplements on infant and child allergic diseases through systematic review and meta-analysis.Design: PubMed, The Cochrane Library and references of related articles published before January 1, 2020 were searched.Setting: Meta-analysis was used to explore the influence of folic acid on skin allergies (eczema, and atopic dermatitis) and respiratory allergies (asthma, wheezing, and allergic rhinitis).Participants: Data were collected from 15 studies with 244,018 individual participants from five different countries for meta-analysis.Results: Folic acid was confirmed as a risk factor for allergic diseases in infant and child. The risk of allergic diseases dramatically increased when maternal folic acid intake
Databáze: Directory of Open Access Journals