| Autor: |
Zhu Cao, Xinxin Wang, Xinxin Wu, Chen Zhu |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Tetrahedron Chem, Vol 4, Iss , Pp 100031- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2666-951X |
| DOI: |
10.1016/j.tchem.2022.100031 |
| Popis: |
A Minisci-type reaction catalyzed by iodobenzene is disclosed here for the first time. The heteroarylation of unprotected aliphatic alcohols proceeds via alkoxy radical-induced homolytic cleavage of C–H and C–C bonds under photochemical conditions. The use of m-CPBA as the oxidant allows the oxidation of iodobenzene to a hypervalent iodine species, driving the catalytic cycle. The method features mild reaction conditions, broad scope of heteroarenes and alcohols, and scaled up preparations. This approach provides a notable supplement to iodobenzene-catalyzed ionic reactions, and opens up a new avenue for its application in radical chemistry. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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