The Effects of Once-Weekly Alendronate 70 mg, Risedronate 35 mg and Raloxifene 60 mg Daily in the Treatment of Postmenopausal Osteoporosis in Turkish Population

Autor: Mesut Öktem, İbrahim Esinler, Derya Eroğlu, Pınar Akkaya, Esra Kuşcu, Hulusi Zeyneloğlu
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Zdroj: Gynecology Obstetrics & Reproductive Medicine, Vol 13, Iss 1 (2007)
Druh dokumentu: article
ISSN: 1300-4751
Popis: OBJECTIVE: We aimed to compare the efficacy and tolerability of once-weekly alendronate 70 mg/weekly, risedronate 35 mg/weekly and raloxifene 60 mg/daily in the treatment of postmenopausal osteoporosis. STUDY DESIGN: Retrospective case-control study. 216 aged matched postmenopausal women with osteoporosis who received alendronate (n=70), risedronate (n=74), or raloxifene (n=72) for 24 months were retrospectively evaluated. Additionally, all patients received 600 mg Calcium+ 400 IU Vit D daily. Bone mineral density (BMD) was measured by dual X-ray absorptiometry. T scores at baseline and 24 months were evaluated in the lumbar spine, total hip, femur neck, and trochanter. RESULTS: Baseline T scores of each region were not significantly different among three groups. T scores increased in the lumbar spine (p
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